BioOne 64oz 2 Bottle Starter Pack for Residential & Commercial Liquid Drain & Septic Tank Maintenance

(66 customer reviews)

USD $109.00

The two pack is a perfect way to jump start the biological action in your septic system. Whether the system is new or newly pumped, add one bottle directly to provide a solid base of bacteria and use the second bottle to treat as recommended.

BioOne is a 100% natural piping & drain line cleaner that eliminates the build-up of fats, oils, grease (FOG) as well as food waste. BioOne is also known for its septic tank, grease trap and leach field maintainer efforts, keeping those systems & tanks clear and clean.

BioOne works by using friendly bacteria that eat their way through waste (a natural biological digestion process), eliminating drain line build up. BioOne is Patented and recognized by the EPA as a safer choice product. We’re proud to carry a product with the Safer Choice Label! BioOne is extremely cost effective due to the high number of 32 doses (regular treatments) per bottle. For years BioOne has been trusted by 1,000’s of commercial plumbers & residential consumers.

  • Recognized by the U.S. EPA Safer Product Standards
  • Recipient of the EPA Safer Choice Partner of the Year Award
  • Made in the USA
  • 1st Microbial Product Recognized
  • Non-Hazardous / Non-Pathogenic
  • Safe for People, Pets & Pipes
  • Trusted by 1,000’s of Professionals & Consumers
  • Patented

Interested in only the single bottle of BioOne for $65? View the BioOne 64oz Single Bottle Product Here.

Interested in Bulk Pricing? Call 828-255-0772 for special pricing on BioOne Liquid by the Case.

SKU: AP-B164-SP Categories: , ,

Product Instructions

Starter Pack (get discounted pricing on multiple bottles!)

The bottle design makes measuring and dosing easy.  32 Treatments per bottle. 

Slow Drains: Treat daily for five consecutive days or until drain flows normally.

Routine Maintenance: Treat all drains once per month.

Applications: drains, septic tanks, leach / drain fields, ejector tanks, grease pits / traps

Additional information

Weight 10 lbs
Dimensions 12 × 8 × 8 in

66 reviews for BioOne 64oz 2 Bottle Starter Pack for Residential & Commercial Liquid Drain & Septic Tank Maintenance

  1. Tim

    Good so far…I pumped my septic tank and followed instructions on the bottle… Now time will for service and delivery, EXCELLENT…

  2. Sarah

    Purchased after thorough research. I’m now a repeat customer We have an unbelievable amount of buildup in the drain just from regular use. This helps keep the drain clearer and definitely fresher-smelling. Will buy again!

  3. Tina

    Introduced to this product by our plumber but could not purchase it or find it any where locally for weeks. Thanks to the excellent service of Aqua Pro and their pricing, including proper shipping packaging and delivery, we are back to maintaining our drains . Thank you very much for all you do to make this product available without any problems or issues.

  4. Nancy Jenkins

    We are very pleased that we received our order promptly.
    We have been using Aqua Pro for some time now and are quite happy with the product and the service that we have received.
    Will continue to utilize this product.

    Thank you.

  5. heidi

    Used the powder version in a former home and it worked wonders on the pipes and saved us loads of emergency plumber calls. So happy with this liquid version to service the pipes in our now home that are cast iron and lead to a septic. Hoping to continue the continuous use with the money savings buying two bottles and keep our pipes clean and clear.

  6. Mark

    Been using this product for a couple of years. Keeps the septic system flowing freely and reduces odors. Delivery was quick. Will continue to purchase this product here


    I originally bought the 64 oz 2/pack for my residence for slow drains…… my drains are now running smoothly. I’ve recently bought the 2.5 gallon 2/pack for monthly maintenance and at a price savings.

  8. Eric

    Great customer service! Had an issue with USPS and they went above and beyond to make sure I got what I ordered. Product looks to be working great. I opened a clean out that I’ve been using the product in and all the build up cleared. Will keep using for preventative.

  9. Connie


  10. Joe Beauchaine

    5 stars

  11. Chelsie

    I only have a 1 month update and didn’t have any cloggs. But from all the research this appeared to be the best option out there. No chemicals and it creates a good bacteria in the pipes. I’m excited and hopeful that’s the case. Wish it was not as expensive.

  12. Michael Kelly

    Excellent company to do business with. Very efficient and timely. Will definitely place another order when needed. Thank you


    Product recommend by my Septic Company. The septic tank needed this product for good bacteria in the system. I have used this product once a month as directed . The cost to repair my septic tank and septic lines was SHOCKING . This is a good prouct.

  14. Geoff

    Like many others, my plumber recommended BioOne added to every drain once a month. I got the first jug from the plumber, but have been buying subsequent product from Aqua Pro. Buying is easy, shipping is quick and I’m a very happy customer.

  15. Adams John W.

    Works as hoped. Cleared out our shower drain without issue.

  16. Justin

    This product came highly recommended by someone who hasn’t had an issue with his septic system in 30 years or so of using this product.
    Product arrived on schedule as expected.
    Add to my system right away. Hoping we have the same results.

  17. Mike

    Leach bed was not working properly and septic tank level kept rising. Put 1/2 gallon directly into clean out for leach bed, and within 10 days everything started flowing properly. Added 6 ounces to line going directly into septic tank. All running fine now. We use bleach and anti bacterial soap in our home, so we will continue using BioOne monthly,

  18. John

    Shipping was really fast and free. I received the package in short time . Just starting to use bio one, hope it helps.
    Aqua pro also has a good value.

  19. Jean C. Lindsey

    May 24, 2023
    We have a mountain house near Florissant, CO. We have both an aerobic and anaerobic system due to our location. We have used Bio One since the early 2000’s. We have only had to have our system pumped out one time, and we have a septic company check our system every two years. We are not year around residents, and of course that makes a big difference, but I certainly rely on Bio One to keep our system in good shape!

  20. Kathy

    Recommended by plumber to unclog lines from house and so far has worked great. No back ups and toilets flushing well.

  21. Jennifer

    Testing it out seems to be working great.. thanks for a great product

  22. Addie Palacios

    Aqua Pro team, Your website provides clear detail around the Bio One drain cleaning product. Thanks!

  23. William Nyquist

    I saw this offer on the website so I thought I would try it. I looked at most of the reviews and didn’t really see someone with my situation. So I am still in a trial period to see if this helps me. I have a sewer ejector, also known as a grinder from Little Giant,. It’s a tank that fills up with sewage then gets pumped out to the town sewer when the floats activate..
    Recently the floats were getting stuck with trapped solids, so I hope this bacteria helps with that problem. If anyone has success with this situation, I would like to hear it? Also would like to know what’s causing the solids build up.
    Thank you

  24. Teresa

    Product was recommended by our contractor. Aqua pro solutions allows for easy access to replenishing product. No hassle and shipped well.

  25. karen stephenson

    Jason was super helpful in making sure I got my product. Many thanks!

  26. john murray

    price is fair been using for several years now and will continue

  27. JF

    I have purchased this product for a friend for the past 3 years. I am very happy with service. Easy ordering process; items ship quickly; and are received in good condition.

  28. Lef

    I have been using this product since 09/2022 and so far it appears to be working to taking care of the odor in my bathroom.

  29. Melody Judd

    Have been using this product for years. It is a great product. The company is very responsive. Sends product quickly. I will continue to order. Thank you.

  30. Dennis & Camille

    We have been using this product for over 8 years and will continue to do so. It is fantastic.

  31. Raymond Sharpless

    Just started using the product the first of November 2022. Excellent delivery service. Will let you know in a couple of years how it is doing as I have no problem at present with my system. Thanks.

  32. Carla Cordova

    I’ve been using this for a few years now and highly recommend it. I bought the two and gave my daughter one. And your price is cheaper than any place I’ve seen

  33. Jaime N Austria

    I used to live in a large city in Virginia, but after I retired and moved to a more rural area, the home I purchased has a septic tank. I asked the septic tank company who does maintenance on my unit what to use and they highly recommended BioOne. I’m glad they did. With this product I had no issues with my unit. Also, we received quick shipment and excellent communication. Highly recommend this vendor, I am a repeat customer.

  34. Diane Fujii

    My friend told me about BioOne, her plumber recommended it to her. The BioOne came just in time, my shower drain started to backup due to my daughters long hair clogging the drain. One application did the trick, the shower drained smoothly.
    I told my friends and family about the BioOne.
    I no long have to unclog my drains with vinegar, baking powder and hot water, this is so simple.
    Thank you, thank you.

  35. Jan O.

    1st time using BioOne 64 oz residential drain cleaner. Purchased as experiment after repeated expensive visits by plumber to snake old clogged sink drain. Took 5 nights of application but drain completely cleared. Certainly worth the money. Now using in all drains on a monthly schedule.

  36. Jessie Norris

    Our plumber recommended BioOne for a situation in our 1909 house in which a 90 degree bend in an old and unreachable drain was causing gunk to collect and then back up in a basement shower stall. We’ve been using it once a month for several years, and have had no problems since.

    Very effective.

  37. Debbie

    Just received product after recommended by my plumber. He said the best thing to use (enzymes). We have septic system and I have already used on the drains and will continue once a month. The only thing I don’t/didn’t like is the foil doesn’t come off really well which causes leaking. Is there an easy way to take off the foil?


    My recent order came for two bottles of BioOne 64oz 2 bottle starter pack. It was packed impeccably and came with perfect communication of when to expect it. This will be my second year of septic use and we have had no issues thank goodness. It is on it’s 22nd year so we are grateful that it contines to tick over not having issues and I believe BioOne is helping.

  39. Cindy S

    This stuff is awesome. Was recommended to me by a plumber and it has eliminated our clogged drain issue! Highly recommend!

  40. waldo.immerson

    Excellent product. No other drain cleaner that I have used does quite the same. And shipping turn around was far superior to even amazon. Outstanding product and service equals a winning combination. Bio one excels in comparison to any of the other drain cleaners I have used on my septic system. Continued maintenance is easy and straight forward. Don’t waste your money on the substandard products offered on any of the other online stores.

  41. Claudia Agentis

    Package arrived quickly and in good condition. This is the only place I could find the BioOne drain cleaner. It works 10X better than anything you find on Amazon and the price is right.

  42. Bruce Marcho

    I’ve heard about this product from my neighbor who was recommended by his plumber. It’s hard to find it outside this site and the starter package has two 64oz bottles. I’ve used it on my septic that has a new drainfield but working only 50% due to overuse. After using the BioOne for a few years, the system is working better. After a pump out, you use one bottle completely. Drop a little in all drains for best results. Then after the first bottle, use the recommended oz once per month for regular maintenance.

  43. Jim Johnson

    Recently had to have my septic tank drain field replaced. I asked the contractor what he thought was the best product to add to the septic tank monthly to keep things working properly. His quick reply was “BioOne” was the ONLY product he recommends to use.
    Him being a professional in this business I believe him.

  44. Mitchell S.

    The plumber we use recommended this drain cleaning product and we haven’t had any problems since then. Very easy to use. Ordering from the website is just as easy and cost effective.

  45. Harvey Hoffenblum

    Recommended by my Plummer, so far it’s working great!

  46. Linda

    Recommended by my plumber, I have used this for a couple of years and it works better than other products. And it’s safe for people and pets, so less to worry about. Easy to order, packaging design makes measuring simple and contained. Highly recommend!

  47. Keith Kolbeck

    Excellent service. We received our product quickly.
    We have had no problems since using this product. The odor from the drain in our kitchen sink has also been eliminated.
    Thank you!!

  48. Pamela R

    Excellent service; fast delivery. Recommended by my plumber to use this product. Found a better price here than what he sells it for. Easy to use once a month.

  49. William Schoell

    Simple and convenient packaging. That makes it more likely the product will be used as per instructions. Prevention is supremely preferable to remediation.

  50. Kris

    We are completely satisfied by how well this product works in our septic tank. It was recommended by my parent’s plumber and I am so glad to have learned of it. We are due to have our tank pumped so we will add one full bottle and treat monthly.

  51. Dennis Conley

    This product is recommended by our plumber to protect our sewer lines and septic tank. We haven’t had a problem since we started using it regularly. Seems to be an excellent product and Ilike the measure and pour design of the bottle.

  52. Spencer Palmer

    So far it seems to be working. I’ll have to use it for about a year to see if it saves me from calling a plumber.

    I bought this after watching Roger Wakefield recommend it on YouTube.

    It may seem silly, but I like that it’s blue because it’s easier for my kids to tell it’s not water or something they should touch.


  53. Beaux

    Does what it’s advertised to do and is not harmful to plumbing or the environment.

  54. John Noreen

    Ive been using this for a few years. The last time I had my septic pumped the guy said whatever you’re doing keep doing it. It looks great.

  55. Steve

    After having a plumber come to the house to open a slow drain, he recommended the use of this product on a regular basis. He said that he uses it at his own home. Who am I to argue with the pros?

  56. Sharyn

    Works great! Having been using and our slow/clogged drains are flowing!

  57. Gar

    Great product, great price. We have used this product for a couple of years with great results.

  58. Denise

    We are very pleased with this product. It was suggested by a plumber when we were having issues with blockage. It worked pretty quick and have used it since for maintenance.

  59. Monroe

    This product was recommended by a plumber and once finished I ordered it through here, and I was very pleased with the shipment of my BioOne and will order again once needed. Thank you for the great service!

  60. Jean

    Great delivery of product. Use for bathtub clogs. Use this off and on.

  61. Alice

    This is an excellent product.

  62. Mike Clover

    TOTALLY SATISFIED: Product works as advertised. Use it monthly in our bathroom sinks + shower drain. Also put some in the basement drain too.

    Customer service is tops. Had a bottle damaged in transit, but Jason sent a replacement immediately.

  63. Nancy

    I moved into this relatively new home 9 months ago. The first month I had moved here my septic was completely blocked. One of the septic people recommended this product. Easy to use and well worth the prevention. No problems since then and I will continue to use it as long as I live here.

  64. Ron Monaco

    Told about your product and used by my plumber to clean out a bad blockage. Took 3 days (as promised) and I immediately ordered 2 more bottles.
    Shipped as promised and easy to use. Now just one day later and clean as a whistle!!

    Now used every 2-3 weeks as a preventative! Thanks,
    Ron Monaco, Lynnwood, WA

  65. Kathy

    The previous owners of our house used BioOne and we have continued for the last 5 years and our septic has had no issues.

  66. Tom

    Have been using this product for over two years without having any drainage issues in our home. Would recommend this to anyone who is looking for a maintenance solution for clogged drains.

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